Chelsea secured a potentially important away goal as they drew 1-1 against Real Madrid.
Timo Werner failed to take a glorious chance to score before Pulisic’s opener as his shot from four yards out was saved.
Werner, who has 11 goals in all competitions for Chelsea this season, scored the winner against West Ham in the Premier League at the weekend but also missed a big chance in that game.
But the Blues boss Thomas Tuchel knows there is plenty more work to do if they are to reach a first final since winning in 2012.
“He missed a big one at West Ham and he missed a big one here but it is nothing to cry about,” Tuchel said.
“This is the best thing about sport, nobody cares tomorrow. He is maybe angry.”
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Real Madrid are 13-time winners of the Champions League but boss Zinedine Zidane accepts his side will have to work hard if they are to keep alive their chances of a 14th title.
The Spanish giants travel to Stamford Bridge for the second leg on Wednesday, 5 May.
